--- product_id: 267971927 title: "Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for X-Large Dogs, Over 55 lbs" brand: "k9 advantix" price: "215.95 DT" currency: TND in_stock: true reviews_count: 5 category: "K9 Advantix" url: https://www.desertcart.tn/products/267971927-bayer-k9-advantix-ii-flea-tick-and-mosquito-prevention-x store_origin: TN region: Tunisia --- # For dogs 55+ lbs Waterproof after 24 hours Kills fleas in 12 hours Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for X-Large Dogs, Over 55 lbs **Brand:** k9 advantix **Price:** 215.95 DT **Availability:** ✅ In Stock ## Summary > 🐾 Protect your big buddy fast — because they deserve the best! ## Quick Answers - **What is this?** Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for X-Large Dogs, Over 55 lbs by k9 advantix - **How much does it cost?** 215.95 DT with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.tn](https://www.desertcart.tn/products/267971927-bayer-k9-advantix-ii-flea-tick-and-mosquito-prevention-x) ## Best For - k9 advantix enthusiasts ## Why This Product - Trusted k9 advantix brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **No Prescription Needed:** Convenient OTC access so your dog stays protected year-round - • **Rapid Flea Elimination:** Kills fleas within 12 hours to stop infestations fast - • **All-in-One Pest Defense:** Repels and kills fleas, ticks, mosquitoes, biting flies, and lice - • **Waterproof & Fragrance-Free:** Enjoy worry-free outdoor adventures with no scent or residue - • **Vet-Recommended & Easy Application:** Topical spot-on treatment applied in seconds, no pills or collars needed ## Overview K9 Advantix II Extra Large Dog is a vet-recommended, topical flea, tick, mosquito, biting fly, and lice treatment for dogs over 55 lbs. It kills fleas within 12 hours and repels pests on contact, is waterproof after 24 hours, fragrance-free, and requires no prescription. Monthly use prevents infestations and protects against pest-borne diseases, making it an essential, easy-to-apply solution for active large dogs. ## Description K9 Advantix II Extra Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Extra Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh over 55 lbs. to use K9 Advantix II Extra Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Extra Large Dog is a trademark of Elanco or its affiliates. Review: It actually works better than I thought. My dog went from scratching and bitting constantly to every now and then. Still see a flea occasionally but nothing like before I used it. Easy to apply. No for. Not sure that it last the full 30 days but I’ll take 20! Review: I love this product! Been buying for years, I only put it on my 3 dogs once, beginning of summer and they are good all year! I also spray my yard too so I’m sure that helps too but won’t use anything else! ## Features - K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice - Kills fleas within 12 hours of application - Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die - Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours - No prescription needed ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B07NX2VWYC | | Active Ingredients | Imidacloprid, Permethrin, Pyriproxyfen | | Age Range Description | 7 weeks and older | | Allergen Information | Allergen-Free | | Brand Name | K9 Advantix | | Customer Reviews | 4.3 4.3 out of 5 stars (5,580) | | Dog Breed Size | Large | | Global Trade Identification Number | 00724089114945 | | Included Components | None | | Item Form | Topical | | Item Type Name | Topical | | Item Weight | 0.05 Pounds | | Manufacturer | K9 Advantix | | Manufacturer Part Number | 90204386 | | Model Number | 90204386 | | Scent Name | Unscented | | Target Species | Dog | | UPC | 724089114945 | | Unit Count | 1 Count | | Volume | 4 Milliliters | ## Product Details - **Active Ingredients:** Imidacloprid, Permethrin, Pyriproxyfen - **Brand:** K9 Advantix - **Item form:** Topical - **Item weight:** 0.05 Pounds - **Scent:** Unscented ## Images ![Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for X-Large Dogs, Over 55 lbs - Image 1](https://m.media-amazon.com/images/I/71TmwfTVSuL.jpg) ## Questions & Answers **Q: Has anyone switched over from Frontline Plus to K9 Advantix II and is happy? For Dogs** A: YES!!!! I've had the same experience with my dogs as Nicole A replied. I had been pleased with Frontline for years....but in 2012 (and ever since) it has just stopped working. One of my dogs is a fur-making machine: and fleas don't seem to bother him...even if I am finding them on him. The other dog has horrible flea allergies: has immediate, sustained, and severe "hot spots" after even just ONE flea bite...skin will turn pink all over his body...and he "blows" large amounts of his beautiful, lush, scruffy coat...and he just doesn't seem to be his usual happy, bright, and enthusiastic self :-( Using Advantix II....he seems to not have problems at all (it keeps the fleas from breeding...although if one occasional transient flea bites him....it will die...but the dog will still get a "hotspot", but nowhere as intense or sustained as without Advantix II...and if I find it quickly and clean it with vinegar, he may not even need a dose of benedryl). During the "flea season" since using Advantix II he has been able to keep his lush coat with no problems.....to such an extent that I brought him in to my vet's office just to show the vet how well he was doing one summer (the dog had been so bad the previous summer while using Frontline that I had to take him to the vet for skin reactions, fur loss in large areas of his coat, and a secondary infection from scratching...I had been so discouraged about the flea problems that year while on Frontline that I had been taking the dog daily to the lake so he could swim and drown the damned fleas). The vet was very pleased with the dog's condition with Advantix II, and had stated he has learned from his patients that they are also seeing less effectiveness with Frontline in recent years. I won't use anything else but Advantix II during this up-coming flea season. (although I do also spray his coat/skin with vinegar (mixed 1/2 with water) each day as a flea deterrent...especially if he gets a hotspot...and I add a small amount of vinegar to his food as well........and when he does need a bath: I use EXTREMELY diluted Dr. Bronner's castile liquid soap in the "EUCALYPTUS" version....the dog tolerates it well...and it seems the scent repels fleas a bit. I use the soap as well to launder the cover of his dog bed at least weekly). I know that insects can get resistent to certain pesticides over time....and I suspect that is why Frontline no longer works in our area.....I sure hope it doesn't eventually happen with Advantix II as well....and I hope that producers of flea/tick products for dogs will monitor this situation and re-formulate their products as needed to address the situation--regionally if need be. **Q: I thought I was ordering Advantage II but by mistake, ordered Advantix II. What is the difference, and does it work the same?** A: You can’t use advantix on cats. sadly because advantix 2 is superior and is the best out there because unlike advantage (and unlike frontline) it repels flies and mosquitoes as well as ticks and fleas. but it is toxic to cats. as cats should be indoors only you shouldn’t need tick/mosquito repellent just flea. DO NOT USE ADVANTIX ON CATS! It is toxic to them **Q: What about cats? I used to use Advantix on my cats with no problems, as suggested by my vet to save money. Has the formula changed?** A: Look at the active ingredients for both the dog & cat formulas; They are exactly the same. Only difference is the dosage size which you can easily look up on the internet & save yourself a ton of money **Q: Could I use this along with a flea/tick collar?** A: As a vet tech we say a flea collar is basically worthless..At most may keep fleas off pets head. If you can buy flea collar at store probably won’t work and even the script only work minimal. Stick to topical like frontline plus, advantage, advantix and oral like Capstar. Flea collars are most always a waste of $. To remove fleas fast simply bathe dog and let dog sit in water…drowning fleas and follow up in few hours with topical if bad infestation. Just a flea or 2 I’d still bathe but topical probably enough. All topicals are water resistant after 24hr ## Customer Reviews ### ⭐⭐⭐⭐ Review *by A***E on 7 May 2026* It actually works better than I thought. My dog went from scratching and bitting constantly to every now and then. Still see a flea occasionally but nothing like before I used it. Easy to apply. No for. Not sure that it last the full 30 days but I’ll take 20! ### ⭐⭐⭐⭐⭐ Review *by S***R on 8 May 2026* I love this product! Been buying for years, I only put it on my 3 dogs once, beginning of summer and they are good all year! I also spray my yard too so I’m sure that helps too but won’t use anything else! ### ⭐⭐⭐⭐⭐ Review *by B***K on 2 April 2026* Only been a few days but I can tell it’s powerful. My husky hangs outside in the middle of florida theirs all sorts of everything here. Other non prescription medicines were too weak for my big dog. He’s 75 pounds and within 1 hour of applying it along his back, the fleas started reacting. The first day he was scratching quite a bit but now it seems he has relief. ## Frequently Bought Together - K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 1-Mo Supply - K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply - K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 1-Mo Supply --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.tn/products/267971927-bayer-k9-advantix-ii-flea-tick-and-mosquito-prevention-x](https://www.desertcart.tn/products/267971927-bayer-k9-advantix-ii-flea-tick-and-mosquito-prevention-x) --- *Product available on Desertcart Tunisia* *Store origin: TN* *Last updated: 2026-06-23*