---
product_id: 345338753
title: "Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for Large Dogs, 21-55 lbs"
brand: "k9 advantix"
price: "814.84 DT"
currency: TND
in_stock: true
reviews_count: 5
category: "K9 Advantix"
url: https://www.desertcart.tn/products/345338753-bayer-k9-advantix-ii-flea-tick-and-mosquito-prevention-large
store_origin: TN
region: Tunisia
---

# For large dogs 21-55 lbs Kills fleas within 12 hours 30-day waterproof protection Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for Large Dogs, 21-55 lbs

**Brand:** k9 advantix
**Price:** 814.84 DT
**Availability:** ✅ In Stock

## Summary

> 🛡️ Keep your best friend bite-free and thriving—because every dog deserves premium protection!

## Quick Answers

- **What is this?** Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for Large Dogs, 21-55 lbs by k9 advantix
- **How much does it cost?** 814.84 DT with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.tn](https://www.desertcart.tn/products/345338753-bayer-k9-advantix-ii-flea-tick-and-mosquito-prevention-large)

## Best For

- k9 advantix enthusiasts

## Why This Product

- Trusted k9 advantix brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Month-Long Shield:** Waterproof formula keeps working for a full 30 days, even after baths or swims.
- • **Rapid Action Defense:** Starts killing fleas in just 12 hours—no waiting, no suffering.
- • **Contact Kill Technology:** Fleas and ticks die on contact—no painful bites needed for protection.
- • **Broad-Spectrum Protection:** Repels and kills fleas, ticks, AND mosquitoes—triple threat coverage.
- • **Vet-Recommended & Trusted:** Clinically proven and highly rated by thousands of dog owners nationwide.

## Overview

Bayer K9 Advantix II is a topical flea, tick, and mosquito prevention treatment designed for large dogs weighing 21-55 lbs. It delivers fast-acting, contact-based pest control that starts killing fleas within 12 hours and provides waterproof protection for up to 30 days. This 6-month supply is veterinarian-recommended and offers broad-spectrum defense, including mosquito repellent benefits not commonly found in similar products.

## Description

The 6-pack of Bayer K9 Advantix II flea and tick prevention for large dogs is a broad-spectrum, veterinarian-recommended dog flea and tick prevention that also kills and repels mosquitoes, a benefit not found in many other flea and tick products. Some products require a flea or tick to bite your dog in order to work, but K9 Advantix II flea and tick prevention for dogs is a topical formula that works through contact, so your dog doesn’t have to endure a painful bite for the flea, tick or mosquito to die. Just one application of Bayer K9 Advantix II flea and tick prevention for large dogs starts working to kill fleas within 12 hours, is waterproof after 24 hours, and continues to work to kill fleas, ticks and mosquitoes for up to 30 days, even after a bath or swimming. We recommend the use of a grooming shampoo designed specifically for pets. Do not use K9 Advantix II on cats. Use only on dogs.

Review: I recently moved from the cooler, mountainous region of SC to the warmer climate of middle GA to attend graduate school. I had been using Comfortis for two and half years on my dog, Fluke, without any problems. However, about two weeks ago, I felt a lump on her neck, and upon inspection, I discovered a tick. I began looking all over her body for more of these little pests, and found four more of them. Fortunately, Fluke is a rescue from a vet, and I don't have to bear the burden of expensive vet bills when something like this situation occurs. I was told that the Comfortis does not necessarily guard against ticks, and while it may have been effective in SC, the tick population in the heavily wooded river area in which I live now might be too much for the tablet to protect against for Fluke. I bought this product because it proffered to prevent ticks from attaching to the dog, and thus far, it has proven quite effective. Fluke, as her name suggests, is an unusual 25 pound lab/pit mixture. I purchased the product in the larger size because she is in between the medium and large dosing sizes, and I wanted to be sure that she had adequate protection. Fluke has been her usual happy self since I applied it to her. The directions indicated that you should apply in four to six spots on the dog, and I chose to apply to six, as to not have too high of a concentration in any area. I know that some people have reported having adverse reactions upon applying this product on their dogs, but I have noticed a trend in the reviews: most of the reviews are concerning smaller dogs. It might be that the formula is just too much for a smaller dog, but I'm not anywhere near an expert on the topic, just something that I have noticed. I am of the opinion that what it boils down to is this: all dogs are different, and what works well for one dog does not necessarily work well for others; the same could be said of medications for people, too. I'm just happy to have chosen a product that works well for Fluke. On another note, if you only need flea prevention, Comfortis is amazing, and much less messy than the topical products. While searching for more ticks, I never did find a flea on her! I hope that my review could be of some help, even though it is not very specific. UPDATE AS OF JULY 2013: I have brought home a 4 pound Pomeranian since my original post. I stand by what I stated in my previous post: this product works well for fleas, ticks, and mites in the warmer climate of middle Georgia in which I live. Barnaby, my little Pomeranian, has not had an adverse reaction to this medication, and Fluke, my lab/pit mixture, remains free of fleas and ticks, all the while not exhibiting any negative symptoms. For my little Pomeranian, I applied the medication to 4 separate places along his back, again to not have too high of a concentration in any one area. I purchased the smallest dose currently on the market, and although it was a little high for his small stature, it did not seem to phase him in any sort of negative ways. I wait, at a minimum, 72 hours before bathing my dogs, and I also do not bathe them for at least 5 days prior to application of the medication, as the oils within a dog's skin distribute the topical treatment. My dogs tolerate this medication well, and I have not found a flea or tick on either of them since I began using this product; however, I still will caution potential purchasers of this product: this product may not work well for your dog, just as some medications may not work well for you. Please, before you condemn the product as unsatisfactory, try to determine, and this may require the aid of a veterinarian, what your particular dog requires based upon breed, climate, and tolerance to topical flea prevention. I can only relate that this product works well for my larger dog and also my smaller dog within the area in which we currently live. Again, I hope that my update as to the effects of this product upon my smaller dog is helpful in your search for the right fit for your dog.
Review: I have used this product for years. I only had a problem with it once and the manufacturer and I could not figure out what the problem was but they stood by there product and forwarded me another box. I have never had another problem with the product and will continue to use it. I live on a farm and we have major insect problems which this product has worked to address.

## Features

- 6 monthly applications of K9 Advantix II flea and tick prevention for large dogs weighing 21-55 pounds
- K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die
- K9 Advantix II flea and tick control for dogs is an easy to apply topical formula
- Starts working to kill fleas within 12 hours and keeps working for 30 days
- Suitable for effective year-round dog flea and tick treatment for large dogs

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B004QN0M2S |
| Batteries Included | No |
| Best Sellers Rank | #43,339 in Pet Supplies ( See Top 100 in Pet Supplies ) #50 in Dog Flea Drops |
| Color | Red |
| Customer Reviews | 4.6 4.6 out of 5 stars (11,223) |
| Date First Available | 7 August 2012 |
| Item Form | Topical |
| Item Weight | 9.07 g |
| Item model number | 86315092 |
| Number of Items | 1 |
| Product Dimensions | 19.69 x 2.54 x 10.8 cm; 9.07 g |
| Quantity | 1 |
| Size | 6-pack |
| Volume | 1 Quarts |
| batteries required | No |

## Product Details

- **Active Ingredients:** Imidacloprid, Permethrin, Pyriproxyfen
- **Brand:** K9 Advantix
- **Item form:** Topical
- **Item volume:** 1 Quarts
- **Item weight:** 0.02 Pounds

## Images

![Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for Large Dogs, 21-55 lbs - Image 1](https://m.media-amazon.com/images/I/71wsnDhKyPL.jpg)

## Questions & Answers

**Q: I am thinking about ordering a 6 pack which some would be kept for next year. How do I know what the date is on the product?**
A: I looked everywhere on the individual package of the tubes and the box, there is nothing that mentions an expiration or use by date. There are phone numbers to call for questions...1-800-255-6826. Looking at how the tubes are packaged, my best guess would be that as long as they are sealed properly and not opened you could probably use unopened tubes at a later time. I have 2 dogs and ordered the six pack myself, if I don't use give my girls all 3 of their doses this year I will probably use it up next summer then.

**Q: What is the expiration date on this $41 product currently for sale???**
A: The expiration date is usually stamped into the package. And $41 is very good price for k9 Advantix II. It's often quite more expensive from your vet or other sites.

**Q: Is this safe for sight hounds and/or dogs over the age of 12? Thank you for taking time to answer.**
A: Yes, there should be no issue when using on a sight hound.  I use this on my Brittney with no issues.  Be advised this does not " repel" ticks.  Ticks will still get onto your dog and can/will bite however, the tick will be impaired/ killed over a few hours time after biting.  When used with a organic spray for Ticks you should have no issues.  I have never had a flea on my dog nor my 2 cats. I recommend this product fully.  Be sure to match your dog's weight with the correct Advantix.

**Q: Does it send all 6 doses at a time?**
A: When you order a 6 pack that means 6 doses.  IF you order a 3 or 4 pack.  it is that many doses respectively.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by A***N on 29 April 2012*

I recently moved from the cooler, mountainous region of SC to the warmer climate of middle GA to attend graduate school. I had been using Comfortis for two and half years on my dog, Fluke, without any problems. However, about two weeks ago, I felt a lump on her neck, and upon inspection, I discovered a tick. I began looking all over her body for more of these little pests, and found four more of them. Fortunately, Fluke is a rescue from a vet, and I don't have to bear the burden of expensive vet bills when something like this situation occurs. I was told that the Comfortis does not necessarily guard against ticks, and while it may have been effective in SC, the tick population in the heavily wooded river area in which I live now might be too much for the tablet to protect against for Fluke. I bought this product because it proffered to prevent ticks from attaching to the dog, and thus far, it has proven quite effective. Fluke, as her name suggests, is an unusual 25 pound lab/pit mixture. I purchased the product in the larger size because she is in between the medium and large dosing sizes, and I wanted to be sure that she had adequate protection. Fluke has been her usual happy self since I applied it to her. The directions indicated that you should apply in four to six spots on the dog, and I chose to apply to six, as to not have too high of a concentration in any area. I know that some people have reported having adverse reactions upon applying this product on their dogs, but I have noticed a trend in the reviews: most of the reviews are concerning smaller dogs. It might be that the formula is just too much for a smaller dog, but I'm not anywhere near an expert on the topic, just something that I have noticed. I am of the opinion that what it boils down to is this: all dogs are different, and what works well for one dog does not necessarily work well for others; the same could be said of medications for people, too. I'm just happy to have chosen a product that works well for Fluke. On another note, if you only need flea prevention, Comfortis is amazing, and much less messy than the topical products. While searching for more ticks, I never did find a flea on her! I hope that my review could be of some help, even though it is not very specific. UPDATE AS OF JULY 2013: I have brought home a 4 pound Pomeranian since my original post. I stand by what I stated in my previous post: this product works well for fleas, ticks, and mites in the warmer climate of middle Georgia in which I live. Barnaby, my little Pomeranian, has not had an adverse reaction to this medication, and Fluke, my lab/pit mixture, remains free of fleas and ticks, all the while not exhibiting any negative symptoms. For my little Pomeranian, I applied the medication to 4 separate places along his back, again to not have too high of a concentration in any one area. I purchased the smallest dose currently on the market, and although it was a little high for his small stature, it did not seem to phase him in any sort of negative ways. I wait, at a minimum, 72 hours before bathing my dogs, and I also do not bathe them for at least 5 days prior to application of the medication, as the oils within a dog's skin distribute the topical treatment. My dogs tolerate this medication well, and I have not found a flea or tick on either of them since I began using this product; however, I still will caution potential purchasers of this product: this product may not work well for your dog, just as some medications may not work well for you. Please, before you condemn the product as unsatisfactory, try to determine, and this may require the aid of a veterinarian, what your particular dog requires based upon breed, climate, and tolerance to topical flea prevention. I can only relate that this product works well for my larger dog and also my smaller dog within the area in which we currently live. Again, I hope that my update as to the effects of this product upon my smaller dog is helpful in your search for the right fit for your dog.

### ⭐⭐⭐⭐⭐ Review
*by A***R on 26 January 2026*

I have used this product for years. I only had a problem with it once and the manufacturer and I could not figure out what the problem was but they stood by there product and forwarded me another box. I have never had another problem with the product and will continue to use it. I live on a farm and we have major insect problems which this product has worked to address.

### ⭐⭐⭐⭐ Review
*by J***. on 11 January 2026*

My ten year old dog has never had fleas or ticks in all the years I have used this product. However, every time I apply it to my dogs back his hair feels extremely greasy and thick until I give my dog a bath. It also causes his back to be very itchy.

## Frequently Bought Together

- K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 6-Mo Supply
- K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 6-Mo Supply
- K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 6-Mo Supply

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---

*Product available on Desertcart Tunisia*
*Store origin: TN*
*Last updated: 2026-03-12*