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🛡️ Protect your pup like a pro—because every dog deserves a pest-free life!
K9 Advantix II Large Dog topical treatment delivers fast-acting, vet-recommended protection against fleas, ticks, mosquitoes, biting flies, and lice for dogs 21-55 lbs. This fragrance-free, waterproof formula kills fleas within 12 hours and repels pests on contact, preventing infestations and disease transmission. Easy to apply and available over the counter in convenient multi-dose packs, it’s the ultimate monthly defense for active dogs in any environment.














| ASIN | B004QN0M2S |
| Active Ingredients | Imidacloprid, Permethrin, Pyriproxyfen |
| Age Range Description | 7 weeks and older |
| Allergen Information | Allergen-Free |
| Best Sellers Rank | #393 in Pet Supplies ( See Top 100 in Pet Supplies ) #4 in Dog Flea Drops |
| Brand | K9 Advantix |
| Brand Name | K9 Advantix |
| Customer Reviews | 4.4 out of 5 stars 44,603 Reviews |
| Global Trade Identification Number | 00724089204028 |
| Item Form | Drops |
| Item Type Name | Topical |
| Item Volume | 1 quarts |
| Item Weight | 9.07 g |
| Manufacturer | Elanco US Inc |
| Manufacturer Part Number | 86315092 |
| Model Number | 86315092 |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Dog |
| UPC | 724089204028 |
| Unit Count | 6 Count |
| Volume | 1 quarts |
A**N
Worked well for Fluke
I recently moved from the cooler, mountainous region of SC to the warmer climate of middle GA to attend graduate school. I had been using Comfortis for two and half years on my dog, Fluke, without any problems. However, about two weeks ago, I felt a lump on her neck, and upon inspection, I discovered a tick. I began looking all over her body for more of these little pests, and found four more of them. Fortunately, Fluke is a rescue from a vet, and I don't have to bear the burden of expensive vet bills when something like this situation occurs. I was told that the Comfortis does not necessarily guard against ticks, and while it may have been effective in SC, the tick population in the heavily wooded river area in which I live now might be too much for the tablet to protect against for Fluke. I bought this product because it proffered to prevent ticks from attaching to the dog, and thus far, it has proven quite effective. Fluke, as her name suggests, is an unusual 25 pound lab/pit mixture. I purchased the product in the larger size because she is in between the medium and large dosing sizes, and I wanted to be sure that she had adequate protection. Fluke has been her usual happy self since I applied it to her. The directions indicated that you should apply in four to six spots on the dog, and I chose to apply to six, as to not have too high of a concentration in any area. I know that some people have reported having adverse reactions upon applying this product on their dogs, but I have noticed a trend in the reviews: most of the reviews are concerning smaller dogs. It might be that the formula is just too much for a smaller dog, but I'm not anywhere near an expert on the topic, just something that I have noticed. I am of the opinion that what it boils down to is this: all dogs are different, and what works well for one dog does not necessarily work well for others; the same could be said of medications for people, too. I'm just happy to have chosen a product that works well for Fluke. On another note, if you only need flea prevention, Comfortis is amazing, and much less messy than the topical products. While searching for more ticks, I never did find a flea on her! I hope that my review could be of some help, even though it is not very specific. UPDATE AS OF JULY 2013: I have brought home a 4 pound Pomeranian since my original post. I stand by what I stated in my previous post: this product works well for fleas, ticks, and mites in the warmer climate of middle Georgia in which I live. Barnaby, my little Pomeranian, has not had an adverse reaction to this medication, and Fluke, my lab/pit mixture, remains free of fleas and ticks, all the while not exhibiting any negative symptoms. For my little Pomeranian, I applied the medication to 4 separate places along his back, again to not have too high of a concentration in any one area. I purchased the smallest dose currently on the market, and although it was a little high for his small stature, it did not seem to phase him in any sort of negative ways. I wait, at a minimum, 72 hours before bathing my dogs, and I also do not bathe them for at least 5 days prior to application of the medication, as the oils within a dog's skin distribute the topical treatment. My dogs tolerate this medication well, and I have not found a flea or tick on either of them since I began using this product; however, I still will caution potential purchasers of this product: this product may not work well for your dog, just as some medications may not work well for you. Please, before you condemn the product as unsatisfactory, try to determine, and this may require the aid of a veterinarian, what your particular dog requires based upon breed, climate, and tolerance to topical flea prevention. I can only relate that this product works well for my larger dog and also my smaller dog within the area in which we currently live. Again, I hope that my update as to the effects of this product upon my smaller dog is helpful in your search for the right fit for your dog.
D**E
If you got flees, order this !
I swear by this stuff , always works within 24 hours . Better than frontline and other flea medication.
H**Y
Recommended
Easy to put on (make sure you wear gloves), the only Flea & Tick we will use on our dogs.
S**4
SIZE MATTERS!!!
I purchased the “Large Dog” size for a 30 pound dog. This should have, IMHO, provided more than adequate coverage for the flea problem he has - but it’s been ~2 weeks and he is still barking at his butt. After some research, I learned that you MUST MAKE SURE that the medicine reaches the SKIN, not just the bottom of the fur next to the skin. And - if your treating a dog with “hot spots” - you may want to hold off and see your vet first because this medicine CAN - not always, but has the potential to further inflame these “hot spots” that itch so badly. Finally, always make sure you apply these drops every month on the same day of the month. And please don’t wait until the poor pooch is so irritated by the fleas that they become difficult to treat. Like my grandmother always said, “an ounce of prevention is worth a pound of cure” and with the heat bearing down on the USA this year, the fleas are out taking a bite out of every unprotected animal out there! Make sure you purchase the correct size for your dog, and if you have an animal that is closer to the heavier side, I’d recommend ordering the next size up, but always ask your vet when in doubt. It’s a good product all in all, but fleas are a problem best resolved sooner, not later. Good luck!
V**E
No more fleas
I have 2 dogs and buy the L and XL size. It works great for both of them. When I first moved into my rental house, I had a flea problem, but since using these and spraying in and around the house, it is under control. Definitely recommend.
W**N
Works well
We have been using this on both of our outside dogs and it works well. Only found 2 ticks, 1 on each dog during the summer and that has been it. Very pleased. Vet said we would not be pleased with this product but so far that isn’t true. His is our 2nd order.
S**.
It works
No ticks on my dog anymore! Even the no Sams will not land on her
A**A
Works, but not amazing
It seems to work, but I expected better results. Application was easy and there were no side effects, which I appreciated. However, I didn't notice a huge difference, so I'm still undecided if I would buy it again.
A**R
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R**K
Taste is bad
My dog vomited when he tested the medicine and I had to throw it away in the garbage
Trustpilot
2 days ago
1 week ago