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🛡️ Keep your cat flea-free and fabulous—because your feline deserves the best!
FRONTLINE Plus Flea & Tick Spot Treatment delivers fast-acting, waterproof protection that kills fleas, eggs, larvae, lice, and ticks for a full 30 days. Trusted by pet owners for over 20 years, this easy-to-apply topical treatment is designed for cats and kittens 8 weeks and older, ensuring comprehensive parasite control and peace of mind.


















| ASIN | B07NF9VV22 |
| Active Ingredients | fipronil and (S)-methoprene |
| Age Range Description | All Life Stages |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #182 in Pet Supplies ( See Top 100 in Pet Supplies ) #2 in Cat Flea Drops |
| Brand | Frontline |
| Brand Name | Frontline |
| Customer Reviews | 4.3 out of 5 stars 50,506 Reviews |
| Dog Breed Size | Small |
| Included Components | Applicator |
| Item Form | Stick |
| Item Type Name | Topical Treatment |
| Item Volume | 8 ml |
| Item Weight | 4.54 g |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer Part Number | 72221 |
| Model Number | 72221 |
| Pet Type | Cat |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Cat |
| UPC | 350604062486 611030624861 |
| Unit Count | 1 Count |
| Volume | 8 ml |
| Warranty Description | If you are not satisfied with Frontline Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842. |
J**T
MEWOW THE FLEAS to stay AWAY
I love this stuff, its great and works fine...however it is very important to apply the product monthly as well as correctly. I have thought for years with the Cats I have had, as well as have been told by several vets and vet techs over the years; that the correct way to apply this product is directly on the skin between the shoulder blades. And to be fair to most of the Vets whom have told me that, for the most part I was successful using that method of application. However, as time went on I found this way to apply Frontline more and more difficult as well as it always seem uncomfortable for the Cat. You can use the space between your Cat's shoulder blades as a guide - BUT - the exact proper application spot is actually higher up - at the base of the skull (or as worded inside the package if your Frontline came with the proper instructions `at the base of the neck'). I was very pleasantly surprised that this method was not only much easier, but that there was also no wasted product...I was able to quickly and easily apply the product to each of our 3 cats. I also noticed right away two things. One, each Cat was pretty much comfortable right away and fine as they were before I applied the product - as if I had not even treated them at all. Two, the product was at a spot the cats could not reach even if they wanted to. I don't know why I had never heard of this application method before, as well as why all of the Frontline (and related products) I had purchased in the past said to apply the product directly onto the skin "Between the shoulder blades". This product is great and does work, but it is very important that you apply the product once every 30 days. I would suggest picking a particular date of the month and sticking with that date each and every month. (If you are ever off by a day or two, that is fine - just remember to try and not let it go over 30 days if possible.) Frontline Plus for Cats is not intended to last longer than 30 days, and while it may for some Cats - I personally would not recommend going past the 30 days. If your Cats have worms, this product will keep off the new fleas yes but will do nothing for worms - you should de-worm your Cats first (if needed) and then start with the Frontline about 3 days after de-worming. Indoor Cats can get worms from fleas, even in a very clean home - from time to time some fleas will get in (whether it's on your shoes or from leaving your doors open, etc). Cats usually get worms from when fleas get on them, and then as the cat as it's grooming itself - the cat ingests the fleas (of course the Cat has no idea this will give them worms - they are just cleaning themselves as Cats do). When a Cat eats fleas or other parasites that can get on them from time to time, they can also get other things if left untreated such as Heartworms which are usually fatal. However there is good news! Just apply Frontline once every 30 days and your Cat will stay Flea and parasite free! Any fleas or anything else that may from time to time get onto your Cat will die right away and be of no risk to your Cat. Also over time any residual fleas will eventually die off and your home will be flea - free! However you must apply this product every 30 days year round to ensure that Fleas do not return to your Cat! Preventing your cat from having fleas will in turn not only make you cat much more comfortable, but will also prevent more serious things such as Tapeworms, Roundworms and Heartworms to name just a few things that can originate from your cat ingesting fleas. These more serious conditions for Cats can be prevented with a monthly flea treatment such as Frontline Plus for example. If your cat or home is for some reason very infested with fleas - you have to address that problem first! Remove the cats from the home and use "Flea Bombs" if needed, at least that's how I have always heard them referred to while the proper term is yes "Flea Fogger" or even "Fumigator". You can also use sprays or other like products for your carpet and furniture. Once the home is flea free and your Cat has been treated at the vet for fleas, then make sure to stick with the Frontline every 30 days thereafter. You can also use the Frontline liquid spray to initially kill fleas on the Cat, or a Flea Shampoo. Also keep in mind if your Cat and home are heavily infested with fleas, you should de-worm your cat as well. For most people, de-worming should only be done by or under the direction of a reputable Veterinarian. However if you have owned Cats for many years and know what meds to buy, you can de-worm cats on your own -BUT- only if you are a VERY experienced Cat owner. You can kill your Cat if you give it the wrong type or too much of a de-wormer as de-wormer is a poison (though it's this poison that kills the worms and is perfectly safe when used properly). Frontline helps to keep your cat healthy and is a great preventative medication for your cat. Frontline can and will help keep your Cat healthy and happy for many years to come! Also keep in mind Frontline does not replace periodic checkups or help your Cat in any way if he or she is injured though it will go a very long way in preventing many Cat illnesses and problems related to fleas, ticks, and common parasites. There is more you can do to keep fleas away too, such as treating your yard (unless you have an apartment or condo, etc.) with Pesticide Granules such as Ortho or whatever brand works for you. I am in the Midwest and I would say twice a year is good for the yard treatment, but in South Carolina where I used to live I would have to treat the yard 3 - 4 times a year. If your Cat is outdoor only, keep the Cat inside for 3 -5 days (personally I would say no less than 5 days if possible - a week is more than enough if you want to be extra sure), the same applies for indoor-outdoor cats. This will give the Pesticide time to get into the ground so that it's not toxic to your Cat or small animals such as birds that your Cats may go after. I also use the Riddex Pest repellers....every little bit helps! And of course most importantly of all, apply the Frontline once every 30 days.
L**E
Cat was not bothered by it. Gets rid of fleas pretty good but need bathing as well to get em all!
Good product but spendy
R**S
Apparently Our House Has Become a Small Animal Management Facility
At this point there is definitely a theme forming around here: cats, dogs, pet supplies, flea prevention, repeat. 😄 This has basically become one of those standard household staples when you have multiple cats and don’t want fleas turning the house into a tiny jumping horror movie. We’ve used FRONTLINE products for a long time, and overall this has worked well for routine flea and tick prevention on our cats. The application process is straightforward, and the tubes are easy enough to use without turning the cat into an angry liquid-covered gremlin for the rest of the evening. One thing I especially like is that the doses are pre-measured and simple to apply directly between the shoulders without needing complicated prep. The product also dries reasonably well afterward and hasn’t caused noticeable issues for our cats during normal use. For multi-pet households, staying ahead of fleas becomes way easier than trying to fight a full infestation later after the bugs establish diplomatic control over the property. 😄 The 6-count pack is also convenient because it lasts a decent amount of time and keeps us from constantly needing reorders every few weeks. Overall, this has been another dependable pet-care staple for keeping cats protected and helping maintain household sanity in a house full of animals.
R**B
Great product that does what it says, especially when used with a Flea Trap.
Pros: trusted brand, easy-to-use applicators Cons: packaging lacks some info, very hard to keep animals from eating it This review is based on my unique experience with this product. I recently found a flea on one of my cats and immediately began to panic. "Does my cat really have fleas?" I was in denial for a few days until I saw another flea on my other cat. The fleas clearly weren't leaving, so this meant war. I went out and purchased several flea traps and realized I should also get some flea medicine to kill any fleas or eggs on the cats, so I came to Amazon. I'm familiar with the Frontline Plus brand so I felt confident in my order. After opening the package, I noticed simple instructions for applying the gel (which is stored in little plastic applicators) to the cats. It was relieving to know I wouldn't have to do any measuring - just 1 disposable applicator per cat. The packaging says not to "let your cats eat" the gel, so if you have multiple cats you will have to separate them for 24 hours or until the gel has dried. It took around 6 hours for it to dry. One frustrating, semi-worrying thing (and the reason my review is 4 stars and not 5) is that there were no instructions on what to do if they cat managed to lick the gel. It simply said "don't let them eat it." If you own a cat, you know they're very wiggly creatures, and that is only exacerbated by the fact that you're trying to pin them down and put some strange smelling liquid at the base of their skull. They're also very flexible creatures, so it became apparent very quickly that it was going to be impossible to stop the cats from licking the gel. If you manage to put it in the right spot just at the base of their skull where they can't lick it, they can still scratch that part of their head with their foot and will end up eating the gel that way. You can imagine at this point, I began to get a little worried, especially with the packaging saying "don't let them eat it" without telling you what to do if they do eat it. After some googling and redditing I realized my cats were safe. The gel is relatively non-toxic as long as you don't give them too much of it. If you follow the minimum age and weight requirements and NEVER give flea medicine meant for dogs to your cat, your furry friend should be fine. Overall, the product does what it says it does. If your cat has fleas, this will help tremendously with wiping them out. I would highly recommend a flea trap for carpeted areas of your home to kill any fleas that managed to jump off of your cat. I was shocked at the amount of fleas the trap picked up. The trap I used was the Victor M230 Ultimate Flea Trap, which you can purchase on Amazon here: http://amzn.to/2b1NfPu
W**S
Works like a champ
Didn’t irritate cats skin. Or cause hair loss, it Doesn’t smell bad and lasts a long time. It definitely keeps the fleas and ticks off even when you live in a wooded area or rural area like me and your cat goes out daily
#**E
Fantastic product (and then it isn’t) when it works
Second year of this product not working. Not sure if it is Amazon storing the medicine in hot buildings or what the problem is. My vet warned me about Amazon quality not being adequate. She was proven correct. Helping feral to friend kitties in the Hisses to Kisses initiative meant sometimes needing this to help them. We also use Capstar, as needed. Last year and this year has been a crap show of zero effectiveness. To include the precious German Shepherd who just wants to enjoy his back yard in his elder years. We use flea traps to indicate if any fleas might have hitched a ride on the dog. Or humans. The weather has increased the fleas a bit. Drier years we have less. If we notice any give his cats, yes, he has cats of his own. And the Hisses to Kisses crew being socialized in doors Frontline. This did not help. After the second year of this issue causing an outbreak have used Adam’s leave in treatment and dawn to comb fleas out. The Frontline has zero effectiveness even though we have used it for several months. The flea comb, Adams to include spray … no carpet and such, plus Capstar to help us curb the isssue. Not even the week of application does the dying off happen. This stuff is not curbing offspring either. Zero IGR effect, meaning insect growth inhibitor forcing the new fleas to be rendered useless. I have spent a ridiculous amount of money to keep this product in stock. Attempt to buy on sale or sub and save. Moving forward am gonna continue using Adams, Dawn which doesn’t deter using IGR but we can only use Adam’s leave in once a week. We don’t dip them fully since they’re still working out their feral tendencies. We use the mix of water and Adam’s in the flea comb. Then the rest of the week use down. I use a regular flea comb with a quart yogurt container with water and the mix, and two flea Combs. One to catch the fleas and one to run the comb along the other comb with the fleas to get them and any hair off into the water. For years Frontline worked amazing on my dog who’s 100 pounds. The up to 88 pounds worked perfectly. Now, he needs a Capstar every few days and we comb his face and shorter hair areas as it’s impossible to use the flea comb. But we have to hose him down if we wanna deal with any hitch hikers. I dislike using this poison, so maybe this is a good thing. I’m so disappointed. I was willing to spend the money to help when needed and this stuff isn’t even working on cats inside who got a hitch hiker flea and of course they made a few new fleas so we have to wait until the cooler weather to do a perfect sweep of everything through cleaning. It’s impossible in warmer months too prevent the sneaky ones who hide on my buddy. We’re gonna try homemade mint water as a deterrent and ween off this product that has not done its job two summers in a row. And these have been the worst in years due to the perfect amount of rain for fleas to propagate outdoors. I use Sally Adler on my legs to help deter them, but being in the donation garden I facilitate where local kitties enjoy the shade makes it impossible to foolproof myself. Sharing the extra details because maybe it’ll help someone else looking for alternative solutions. My guess is it’s the warehouse storage in warmer climates that depletes the products ability to do its job. Application should kill off fleas and it is not. This said, I wouldn’t change a thing helping the community kitties and partnering with animal care and control who help foster, vet, and find homes for the friendlies. Hike I help get them to this point and we help do vet care during this process. Which needs to include flea mitigation for new enrollees. Or, like happened last year we have an outbreak and should be able to use a product like this to help solve the issue. No bueno. I realize the company may not recognize the issue with storage and how Amazon transports stuff cannot avoid heat. But you need to work that out because you are losing my purchase. I store ours in the basement where it doesn’t get got and maintains a perfect temp all year round. Do better and I’ll reconsider. Until then, just nope /\ update Having used Frontline for years during warmer months never had an issue until this year. Whether for the German Sheppard needing a dose of the up to 88 pounds has worked even though he’s a hundred. The cat variety has helped kitties to fluffy cats. This year is the worst flea year I’ve ever seen. Based on research the weather is a perfect storm for these pests to grow in number and hope on pants not just cats. We help feral and stray kitties who have a catio with condos for their enjoyment indoors, and one who goes inside at night and outside during the day. Plus a few indoor who have their own room. The Frontline has helped manage the fleas in the past, but not perfectly this year. I’m not sure why a medium sized four month old short hair kitten, despite having had Frontline still accumulates fleas. We’ve tried bathing it’s Adams high did not work. And Capstar. But these depend on the cat being bit. So she gets a flea comb daily. First, we are being fastidious about cleaning and have no clue, how she is getting new fleas. The other cats haven’t had any comb out. Thought it was her playing with the indoor outdoor friend. But he is clear when combed. We haven’t been able to eliminate them all in the Catio where the feral and stray kitties respite. Upon research learned it could take a few months to break the flea cycle. But we still have them trying to bother two in there, too. Not all, but two in particular. So we use Capstar weekly as needed, to help. Plus flea traps ork well, too. In the winter leaving the window open when it’s in the 30’s and 40’s helps act as a flea bomb. As they die off at that temp. This works for most, not all cats this year. Hoping with different weather the population will die off and the new batch of Frontline will help. Might have been a weak batch maybe? The vet made a comment buying off Amazon might lend to poor quality. Until now that was not the case. We will monitor the problem through the fall and winter. If we have no change will find a new product. We buy quite a bit of this and until now have and perfect success. Though not fond of the poison needed for the warmer months it is imperative to manage the flea potential invasion. We are also looking into alternatives. Like move flea comb use and holistic options. Such as projects like “No-Bite-Me™ Bug Repellent & Itch Relief Cream by SallyeAnder” This stuff works fantastic on me, like while boondock camping. Kept chiggers at bay. Except the area I did not use it covered by my shirt on my midsection. We were in the Tennessee wilderness and not one tick on me or my dog. But the chiggers did there worst to my stomach area. I’ve use this on the kitties and it helped. I’ve gotten some ideas from Veterinary Secrets on YT, too. Sharing my negative experience in case someone else went through this. Hope the information helps with alternatives. And know, sometimes during certain weather patterns fleas can increase. And even attack people off the ground. Encourage doing research. Saving up for sales. Using sub and save for monthly savings options. And know this product itself cannot prevent fleas. It is a multi step process. From a cleaning of the house to adding supplements like flea traps for stragglers that get away. A flea comb. Do not wash the cat for a while following application. Look at directions for full details on this. Or you’ll wash off the product. All in all this is my go to supplement to fight fleas outdoors. And if they hit a ride into the house trying to wreck havoc will treat everyone for several months or until they disappear. This is the first year we have to do this. But I’m glad we have a system set up with options. The sales and sub and save price for this product are helpful. The vet suggesting buying on Amazon compared to from them means the product is potentially inferior when the same product when I’ve not has issues for years makes me feel they wanna upsell. Even though they’re a farm vet and cost less than city vets, still made me think proof is in the outcome. Hope this info helps others find solutions to the flea cycle problems that are a part of life with fur friends
M**H
Did its job.
Worked well, but going to re-order another round just in case. My mom has three cats so this only covers one month for her. Easy to apply. Didn’t seem to irritate them. Wasn’t sticky like I thought it would be.
L**D
Think about it twice
I have put it on my cat twice and follow the instructions to the letter like it said and with this product she still has fleas not as many and she's an indoor cat so I was a little disappointed
M**A
The product may be harmful to the cat's skin
The day after applying it my cat lost hair in the area affected by the product. his skin is all irritated
O**W
Counterfeit - do not buy!
Counterfeit product, do not buy Issues included: - 1 of the 4 boxes contained doses labelled as Frontline Plus for dogs - and the lot numbers for the dog and cat does were all the same (all Lot X61002), none of which corresponded with the lot number on the boxes (all X41604AW) - There was no expiry dates on any doses - All 4 boxes were printed with "For dog use only" on the side - The security stickers do not show small rings, which is characteristic of the security stickers from Boehringer Ingelheim - When opening the boxes, there was no tearing along the seams as the legitimate ones should - one of the inserts referred to dogs (with stickers for monthly reminders), and the opposite side had more info for cats (but not a sticker page)
D**Y
Ok
Ok
O**.
Fake Product
Fake product, no expiry day on box and product. Original product have expiry date on it.
K**T
NOT TICK CONTROL
States tick control in picture - box that arrived was not tick control. This is flea control only.
Trustpilot
1 month ago
1 month ago