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❄️ Soothe the itch, own the day—cool confidence in every squeeze!
E45 Itch Relief Gel is a clinically proven, fragrance-free gel designed to instantly soothe, cool, and moisturize dry, itchy, and irritated skin. Formulated with Glycerin and Vitamin B5, it offers lightweight, fast-absorbing relief suitable for face, body, and hands. Trusted for over 60 years, this gel is perfect for sensitive skin and safe for the whole family, delivering dermatologist-backed care that fits seamlessly into your daily routine.













| ASIN | B0BS413MFJ |
| Active Ingredients | acrylates,glycerin,panthenol,sodium gluconate,vitamin b5 |
| Active ingredients | acrylates,glycerin,panthenol,sodium gluconate,vitamin b5 |
| Age Range Description | Adult |
| Age range (description) | Adult |
| Benefits | Relieves Itching |
| Best Sellers Rank | 1,304 in Beauty ( See Top 100 in Beauty ) 5 in Face Day Care Gels |
| Brand | E45 |
| Brand Name | E45 |
| Container Type | Tube |
| Customer Reviews | 4.5 out of 5 stars 995 Reviews |
| Item Dimensions | 32 x 32 x 35 millimetres |
| Item Form | Gel |
| Item Volume | 100 Millilitres |
| Item Weight | 120 Grams |
| Item dimensions L x W x H | 32 x 32 x 35 millimetres |
| Item volume | 100 Millilitres |
| Manufacturer | E45 |
| Manufacturer Contact Information | Karo Pharma UK Ltd, The Pearce Building, 4th Floor, West Street, Maidenhead, SL6 1RL. |
| Manufacturer Part Number | 042026 |
| Model Name | E45 Itch Relief Gel 100ml – Face and Body Gel for Dry Skinm Itchy Skin and Irritated Skin - Cooling Gel to Soothe Itchy Skin - Perfume-Free |
| Number of Items | 1 |
| Other Special Features of the Product | Clinically Proven |
| Scent Name | fragrance free |
| Skin Type | Dry |
| Special Ingredients | Glycerin |
| Special feature | Clinically Proven |
| Specific Uses For Product | Eczema,Psoriasis |
| Target Use Body Part | Whole Body |
| Unit Count | 100.0 millilitre |
M**T
Type 1 diabetic approved
Brilliant! I got eaten alive on holiday, all around my ankles and feet, as a type 1 diabetic this isnt good news. Slapped this stuff on and what a difference it makes. Very cooling, without being menthol. Gel texture. Gentle on broken skin.
J**S
Instant relief
As soon as the posting handed it to me I put it on my leg as I have had some serious skin irritation and the itching is intense to the point I would scratch till I bled. This product is a winner and I truly recommend it. It worked almost instantly. It gave me instant relief and calm. It went on smoothly and absorbed into the skin. I will definitely buy this again. I have had several different creams, lotions and gels from Doctor and all they did was dry my skin and after moment the itch would be there, I couldn't concentrate on anything as it was so bothersome. I can't rave about this product enough. Don't stall, buy it and try it yourself...It works for me and I hope it works for you..Good Luck.
A**Y
Great for the skin.
It is so easy to use and very good for the skin. And it is also very effective for itchy skin me and my wife are very happy with it.
C**E
Good product!
Does exactly as it says on the tin!
U**U
Works really fast on UV reaction.
I am allergic to UV after years on certain meds. Little bit of sun and I itch like mad. After sun has always been useless and then I found this on amazon. Use E45 products so thought would try it and it stops the sun itch instantly. I usually do not even have to put on again. Really settles my skin down fast. Not sure if would help really bad rash as had drug reaction few years ago and nothing helped then but that was super angry. This and E45 with evening primrose been great for my hormonal skin issues as well.
A**2
Lifesaver
I bought this for my mum, who started experiencing skin issues during menopause – her skin was burning and itchy, and we weren’t sure what was causing it. This gel has been a real lifesaver. It’s soothing and cooling, and it genuinely provided her with relief, especially at night when the itching was keeping her awake. She’s much more comfortable now, and it’s made a big difference to her day-to-day comfort. Highly recommended for anyone dealing with dry, irritated, or itchy skin.
C**E
Helps itchy skin
I use it mainly for my hands after washing them it helps soothe the itchiness. Nothing else works for me.
M**J
Did not work
Did not really work for me disappointed
S**H
Sticky
Sticky on hands
Trustpilot
3 weeks ago
1 day ago