Description Comfortis is a chewable medication prescribed by veterinarians for dogs and cats to help treat -- and possibly even prevent -- flea infestations for up to one month. These flavored tablets can be added to your pet's favorite food and only need to be given to your canine companion once a month to help combat fleas. Uses Comfortis kills fleas and is indicated for the prevention and treatment of flea infestations, for one month, on cats and kittens 14 weeks of age and older and 4.1 pounds of body weight or greater. Possible Side Effects The most common side effect reported in dogs is vomiting. Drug & Food Interactions There are no known drug interactions while using Comfortis. Precautions Comfortis chewable tablets are for use in dogs and puppies 14 weeks of age and older. Use with caution in breeding females. Use with caution in dogs with pre-existing epilepsy. The safe use of Comfortis chewable tablets in breeding males has not been evaluated. Prescribing Information See all items by Comfortis Watch our Comfortis video Item Number 146125 Dosage Measure Use according to your veterinarian's instructions. Generic Name Spinosad Common Brand Name(s) Comfortis, Trifexis For Use With Dogs Brand Elanco Breed Size Large Breeds Product Form Chewable Tablet Health Condition Fleas Drug Type Parasiticide Ingredients Ingredients Spinosad Instructions Recommended Dosage Dose varies based on pet's weight. Use according to your veterinarian's instructions. Comfortis is generally given once a month, but you should always follow your veterinarian's directions. It is recommended to give Comfortis chewable tablets with food. Storage Instructions Store at temperatures between 68° - 77°F. Comfortis is given orally once a month. FAQ What are Comfortis (Spinosad) Tablets? They’re beef-flavored, chewable tablets you give to your dog to kill fleas and prevent flea infestations for one month. Comfortis chewable tablets are recommended for monthly use in dogs 14 weeks of age or older and 5 lbs of body weight or greater. What is Spinosad? Spinosad is the active ingredient in Comfortis. It belongs to a class of antiparasitics known as spinosyns, which are derived from a naturally-occurring soil microbe. It works by attacking the nervous system of insects, causing the rapid death of adult fleas. When should treatment with Comfortis begin? Treatment can begin at any time of the year. Comfortis is most effective when given one month before fleas become active, with continued monthly dosing through the end of the flea season. In areas where fleas are common year-round, monthly treatment with Comfortis chewable tablets should continue through the entire year without interruption. To minimize the likelihood of flea re-infestation, simultaneously treat all animals in your household with an approved flea protection product. Consult your veterinarian for the flea treatment options most appropriate for your area. See also, what should I discuss with my veterinarian regarding Comfortis for my dog? How quickly will Comfortis (Spinosad) kill fleas? Spinosad, the active ingredient in Comfortis, began killing fleas in 30 minutes and killed 100% of fleas on dogs in just four hours in controlled laboratory studies. Comfortis chewable tablets kill fleas before they can lay eggs. How long does Comfortis last? Comfortis has demonstrated full effectiveness for an entire month. Does seeing fleas on my dog mean the treatment isn't working? Comfortis kills fleas before they can lay eggs when used monthly, according to the label directions. If you see fleas on your dog within a month after your pet receives Comfortis, they are most likely new fleas. Because your pet has been treated with Comfortis, these new fleas will be killed before they can produce eggs that contaminate your home. Continued monthly use of Comfortis can prevent any new flea infestations. Your pet can experience continued exposure to fleas living in the environment. It’s important to treat all animals
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